22 Zepbound Clinics in San Francisco, California

About Zepbound

Zepbound is a weekly injection from Eli Lilly that helps you lose weight by reducing appetite and slowing how fast your stomach empties. The FDA approved it in November 2023 for adults whose weight is affecting their health. It uses the same active ingredient as Mounjaro (which is approved for type 2 diabetes), but Zepbound is the version specifically labeled for weight loss. In the main study (called SURMOUNT-1), people on the highest dose lost about 22.5% of their starting body weight over about 17 months. For a 200-pound person, that's roughly 45 pounds.

Expected Weight Loss

In the main weight loss trial, people on the highest dose (15 mg) lost an average of 22.5% of their body weight over about 17 months. That is more than any other FDA-approved weight loss medication. About half of participants on 15 mg lost at least 20% of their body weight. For a 200-pound person, 22.5% is roughly 45 pounds. Lower doses also work: 5 mg averaged about 15% and 10 mg averaged about 19.5%. Results vary a lot from person to person.

Cost

Without insurance, Zepbound typically costs About $1,086 per month at retail pharmacies (list price). With insurance, costs range from As low as $25 per month with the Zepbound Savings Card if your commercial insurance covers it.