38 Semaglutide Clinics in South Carolina
Review Semaglutide clinics in South Carolina, including providers offering Ozempic, Wegovy, and Rybelsus for weight loss. Each listing shows rating, medication availability, telehealth options, and provider contact details so you can compare before booking.
How listings are built
Data is compiled from Google Business Profiles and clinic websites using automated research tools. Medication confirmed means medication names were found on the clinic's own website. Claimed means the clinic owner actively manages this page and has verified their details. Fields labeled “owner-provided” were updated directly by the practice.
Rankings on directory pages are based on Google rating, data completeness, and review count. Paid placement is always labeled Sponsored and does not affect organic rankings. Full methodology →
Cities with Semaglutide providers in South Carolina
All Semaglutide clinics in South Carolina
Sponsored listings may appear first in default sorting. Ratings, reviews, and medication data are not affected by paid placement. How rankings work
What the badges mean
Full ranking methodology → • Pricing and medications can change. Always confirm with the clinic directly.
Better Beauty and Wellness, LLC
Restore Hyper Wellness
The Drip Lounge
Physician's Plan
Physician's Plan
Charleston Hormone Services (CHS)
Monarch Esthetics
Serotonin Centers
Gameday Men's Health Charleston, SC
Solcara Health
Physician's Plan
Anew You Aesthetics And Med Spa
Gameday Men's Health Goose Creek
Charleston Healthspan Institute
Metabolic Medical Center
Metabolic Medical Centers
Carolina Trim Clinic
The Drip Lounge Wellness Center
Renew Vitality Testosterone Clinic of North Charleston
Renew Vitality Testosterone Clinic of Charleston
Forest Acres Well Care (Columbia)
Hydrate Medical (Fort Mill)
Lifestyle Physicians LLC
Holy City Health Consultants
Nason MedSpa: Weight Loss
Charleston Pain Relief Center
Slim Rx Medical Weight Loss
Shine Medical Spa by Plastic Surgery of the Carolinas
Charleston Thyroid Center
The Bariatric Clinic
West Ashley Wellness and Rehab
The Wellness Loft
Aqua Vitae - North Charleston, SC
Better Life Carolinas
NasonCare
Totality Medispa (Daniel Island)
What to look for in a Semaglutide clinic
- Brand versus compounded. Some clinics offer brand Ozempic, Wegovy, Rybelsus; others offer compounded Semaglutide. Ask which one. The cost, oversight, and experience differ.
- Dose titration plan. Semaglutide is titrated up over weeks. Confirm the clinic handles dose increases without extra visit fees.
- Insurance versus cash pay. Brand coverage depends on your plan and indication. Compounded Semaglutide is usually cash pay.
- Follow-up and monitoring. Ask what labs, weigh-ins, or check-ins are included in the monthly program.
About Semaglutide in South Carolina
What is Semaglutide?
Semaglutide is the active ingredient in Ozempic, Wegovy, and Rybelsus. It works by copying a natural hunger hormone called GLP-1, which tells your brain you are full and slows digestion. Novo Nordisk originally developed it for type 2 diabetes (Ozempic, 2017), then got it approved at a higher dose for weight loss (Wegovy, 2021). In March 2026, an even higher dose called Wegovy HD was approved. Semaglutide is the most widely prescribed GLP-1 medication in the world, with clinical trials showing 15 to 17% average body weight loss.
Brand names
Semaglutide is available as Ozempic, Wegovy, Rybelsus, manufactured by Novo Nordisk.
Expected weight loss
In the main weight loss trial, people on Wegovy 2.4 mg lost about 14.9% of their body weight over 68 weeks (about 16 months). About one in three lost 20% or more. For a 200-pound person, 15% is roughly 30 pounds. Results vary from person to person depending on dose, diet, exercise, and how your body responds.
Cost in South Carolina
Without insurance, Semaglutide typically costs $800-$1,200/month (Ozempic), $1,300-$1,400/month (Wegovy). With insurance, costs range from $25-$200/month (varies by plan). Compounded options may be available at $200-$500/month.
Savings programs: Novo Nordisk offers savings cards for eligible commercially insured patients. NovoCare patient assistance program available for uninsured/underinsured patients.
Frequently asked questions
There are 38 clinics prescribing Semaglutide (Ozempic and Wegovy and Rybelsus) in South Carolina. South Carolina is one of the better-served states for Semaglutide availability.
Yes, 20 of 38 Semaglutide providers in South Carolina (53%) offer telehealth. Most providers here support virtual visits, so you can start treatment without an office visit.
Brand-name Ozempic and Wegovy and Rybelsus costs $800–$1,400/month without insurance in South Carolina. Compounded Semaglutide from clinic weight loss programs typically runs $200–$500/month. With insurance, copays range from $25–$200/month depending on your plan's formulary and whether prior authorization is required.
Yes. Semaglutide is a prescription medication in all US states including South Carolina. You can get evaluated and prescribed through 20 telehealth providers in South Carolina, or visit any of the 38 clinics listed here in person.
Coverage depends on your plan and diagnosis. Semaglutide is widely covered for type 2 diabetes. For weight management, coverage is expanding. Wegovy and Zepbound now have broader approval, but many plans still require prior authorization or documented BMI criteria. Check with your insurer or ask the clinic to verify coverage before your appointment.
Related articles
Ozempic vs Wegovy: What's the Difference?
Both contain semaglutide, but they're FDA-approved for different purposes. Here's what you need to know before choosing between them.
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The FDA issued a warning letter to Novo Nordisk over unreported potential side effects. Here is what it actually means for patients taking Ozempic or Wegovy.
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