Tirzepatide is a first-in-class dual GIP/GLP-1 receptor agonist developed by Eli Lilly. It uniquely targets both the GIP and GLP-1 receptors, producing greater weight loss and blood sugar control than GLP-1-only medications. Approved as Mounjaro for type 2 diabetes (2022) and Zepbound for weight management (2023), tirzepatide has shown weight loss of up to 22.5% in clinical trials — the highest of any GLP-1 class medication.

Brand Names

Tirzepatide is available as Mounjaro, Zepbound, manufactured by Eli Lilly.

Expected Weight Loss

In the SURMOUNT-1 trial, participants on tirzepatide 15 mg lost an average of 22.5% of their body weight over 72 weeks. At the 10 mg dose, average weight loss was 21.4%. Over a third (36%) on the highest dose lost 25% or more of their body weight, and 63% lost 20% or more.

Cost in New York

Without insurance, Tirzepatide typically costs $1,000-$1,200/month (Mounjaro), $1,000-$1,100/month (Zepbound). With insurance, costs range from $25-$200/month (varies by plan). Compounded options may be available at $250-$550/month.

Savings programs: Eli Lilly offers the Zepbound Savings Card (commercially insured patients may pay as low as $25/month) and the LillyDirect platform for direct-to-patient delivery.

Frequently Asked Questions

How many Tirzepatide clinics are in New York?

There are 49 clinics prescribing Tirzepatide (Mounjaro and Zepbound) in New York. New York is one of the better-served states for Tirzepatide availability.

Can I get Tirzepatide through telehealth in New York?

Yes, 39 of 49 Tirzepatide providers in New York (80%) offer telehealth. Most providers here support virtual visits, so you can start treatment without an office visit.

How much does Tirzepatide cost in New York?

Brand-name Mounjaro and Zepbound costs $800–$1,400/month without insurance in New York. Compounded Tirzepatide from clinic weight loss programs typically runs $200–$500/month. With insurance, copays range from $25–$200/month depending on your plan's formulary and whether prior authorization is required.

Do I need a prescription for Tirzepatide in New York?

Yes. Tirzepatide is a prescription medication in all US states including New York. You can get evaluated and prescribed through 39 telehealth providers in New York, or visit any of the 49 clinics listed here in person.

Does insurance cover Tirzepatide in New York?

Coverage depends on your plan and diagnosis. Tirzepatide is widely covered for type 2 diabetes. For weight management, coverage is expanding — Wegovy and Zepbound now have broader approval, but many plans still require prior authorization or documented BMI criteria. Check with your insurer or ask the clinic to verify coverage before your appointment.

medications