22 Tirzepatide Clinics in South Dakota
Review Tirzepatide clinics in South Dakota, including providers offering Mounjaro and Zepbound for weight loss. Each listing shows rating, medication availability, telehealth options, and provider contact details so you can compare before booking.
How listings are built
Data is compiled from Google Business Profiles and clinic websites using automated research tools. Medication confirmed means medication names were found on the clinic's own website. Claimed means the clinic owner actively manages this page and has verified their details. Fields labeled “owner-provided” were updated directly by the practice.
Rankings on directory pages are based on Google rating, data completeness, and review count. Paid placement is always labeled Sponsored and does not affect organic rankings. Full methodology →
Cities with Tirzepatide providers in South Dakota
All Tirzepatide clinics in South Dakota
Sponsored listings may appear first in default sorting. Ratings, reviews, and medication data are not affected by paid placement. How rankings work
What the badges mean
Full ranking methodology → • Pricing and medications can change. Always confirm with the clinic directly.
Remedy 605
LIVE Hydration Spa Sioux Falls
Refined Aesthetics
Cicily's Aesthetics
Nutrishop
Novo Aesthetics
Black Hills IV Wellness Spa
The Confidence Collective
Gameday Men's Health Sioux Falls TRT, Peptide, and ED Clinic
Era Health
SummaUp
Monument Health Rapid City Clinic, Flormann Street
Monument Health General Surgery and Bariatrics
Health Concepts
EVOLVE Strength & Nutrition Coaching
Sioux Falls Hypnosis
Pure Medical Aesthetics, PLLC
Trillion Health and Hormone Clinic
Accelerate Wellness - Longevity Medicine Clinic
Limitless Male Medical Clinic
What to look for in a Tirzepatide clinic
- Brand versus compounded. Some clinics offer brand Mounjaro, Zepbound; others offer compounded Tirzepatide. Ask which one. The cost, oversight, and experience differ.
- Dose titration plan. Tirzepatide is titrated up over weeks. Confirm the clinic handles dose increases without extra visit fees.
- Insurance versus cash pay. Brand coverage depends on your plan and indication. Compounded Tirzepatide is usually cash pay.
- Follow-up and monitoring. Ask what labs, weigh-ins, or check-ins are included in the monthly program.
About Tirzepatide in South Dakota
What is Tirzepatide?
Tirzepatide is the active ingredient in Mounjaro (for type 2 diabetes) and Zepbound (for weight loss). It is the first medication that targets two hunger hormones at once: GIP and GLP-1. By activating both, it produces stronger weight loss and blood sugar control than older GLP-1-only medications like semaglutide. In the largest clinical trial, people on the highest dose lost an average of 22.5% of their body weight, more than any other FDA-approved weight loss drug.
Brand names
Tirzepatide is available as Mounjaro, Zepbound, manufactured by Eli Lilly.
Expected weight loss
In the main weight loss trial, people on tirzepatide 15 mg lost an average of 22.5% of their body weight over 72 weeks (about 17 months). At 10 mg, the average was 21.4%. Over a third of people on the highest dose lost 25% or more. For a 200-pound person, 22.5% is roughly 45 pounds.
Cost in South Dakota
Without insurance, Tirzepatide typically costs $1,000-$1,200/month (Mounjaro), $1,000-$1,100/month (Zepbound). With insurance, costs range from $25-$200/month (varies by plan). Compounded options may be available at $250-$550/month.
Savings programs: Eli Lilly offers the Zepbound Savings Card (commercially insured patients may pay as low as $25/month) and the LillyDirect platform for direct-to-patient delivery.
Frequently asked questions
There are 22 clinics prescribing Tirzepatide (Mounjaro and Zepbound) in South Dakota. South Dakota is one of the better-served states for Tirzepatide availability.
Yes, 17 of 22 Tirzepatide providers in South Dakota (77%) offer telehealth. Most providers here support virtual visits, so you can start treatment without an office visit.
Brand-name Mounjaro and Zepbound costs $800–$1,400/month without insurance in South Dakota. Compounded Tirzepatide from clinic weight loss programs typically runs $200–$500/month. With insurance, copays range from $25–$200/month depending on your plan's formulary and whether prior authorization is required.
Yes. Tirzepatide is a prescription medication in all US states including South Dakota. You can get evaluated and prescribed through 17 telehealth providers in South Dakota, or visit any of the 22 clinics listed here in person.
Coverage depends on your plan and diagnosis. Tirzepatide is widely covered for type 2 diabetes. For weight management, coverage is expanding. Wegovy and Zepbound now have broader approval, but many plans still require prior authorization or documented BMI criteria. Check with your insurer or ask the clinic to verify coverage before your appointment.
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