21 GLP-1 Clinics in Sioux Falls, South Dakota (2026)
Sioux Falls, South Dakota has 21 GLP-1 clinics averaging 4.8 stars. 10 of them (48%) offer telehealth. The most commonly prescribed medications are Semaglutide (11), Tirzepatide (11), Liraglutide (1). Monthly pricing starts at $200.
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Top Picks in Sioux Falls
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Full ranking methodology → • Pricing and medications can change. Always confirm with the clinic directly.
LIVE Hydration Spa Sioux Falls
Refined Aesthetics
Encompass Wellness & Aesthetics
Novo Aesthetics
The Confidence Collective
Gameday Men's Health Sioux Falls TRT, Peptide, and ED Clinic
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Era Health
Radiant Health and Hormone Therapy
The Retreat at Cedar Creek
Sanford Weight Management Center
Hormones Gone Wild
SummaUp
Sioux Falls Hypnosis
Trillion Health and Hormone Clinic
Profile Plan - Personalized Weight Loss Plans (Virtual Location)
Sioux Falls Secret for Weight Loss
LaVie Ideal Protein Virtual Clinic
Accelerate Wellness - Longevity Medicine Clinic
ekin Nutrition Sioux Falls
Limitless Male Medical Clinic
Avera Comprehensive Weight Management — 41st & Holbrook
Sioux Falls GLP-1 Market Snapshot
Sioux Falls is home to 21 of the 40 GLP-1 clinics tracked in South Dakota — about 53% of the state's directory.
10 clinics offer telehealth (48%), roughly in line with the South Dakota average of 53%. Between them, Sioux Falls providers cover 3 distinct GLP-1 medications.
Frequently Asked Questions About GLP-1 Clinics in Sioux Falls
There are currently 21 GLP-1 weight loss clinics listed in Sioux Falls, South Dakota on GlobalGLP1.com. These clinics offer medications like Semaglutide, Tirzepatide, Liraglutide for long-term weight management.
Clinics in Sioux Falls commonly offer Semaglutide, Tirzepatide, Liraglutide. Contact individual clinics to confirm specific medication availability and pricing.
Yes, 10 out of 21 GLP-1 clinics in Sioux Falls offer telehealth consultations. This means you can talk to a provider from home.
Pricing varies between clinics in Sioux Falls. Brand-name prices without insurance depend on the drug, the dose and where you fill the prescription, and both drug makers now sell some doses directly to cash-paying patients for less than the list price. Compounded versions are not FDA-approved, and since the shortages ended compounding pharmacies generally may not make copies of these drugs, with narrow exceptions. Contact clinics directly for current pricing since rates change frequently.
Source: FDA compounding policy statement, updated April 1, 2026
Sioux Falls has both options. 10 of 21 listed clinics (48%) offer telehealth, and 21 offer in-person visits — some offer both. Telehealth is convenient for follow-ups and medication management once you're established. In-person is usually better for an initial evaluation if you have other health conditions or want a physical exam. Either way, a licensed provider needs to assess your eligibility before prescribing.
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