Weight Loss Clinics in South Dakota
Find providers offering Ozempic, Wegovy, Mounjaro, Zepbound, and other GLP-1 medications in South Dakota. Compare ratings, check telehealth availability, and contact clinics directly.
Cities in South Dakota
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All Clinics in South Dakota
Sorted by patient rating, then data completeness. Featured clinics (paid) shown first when present. How we rank
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Encompass Wellness & Aesthetics
Novo Aesthetics
Sanford Weight Management Center
The Confidence Collective
Gameday Men's Health Sioux Falls TRT, Peptide, and ED Clinic
The Retreat at Cedar Creek
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Era Health
Refined Aesthetics
LIVE Hydration Spa Sioux Falls
Hormones Gone Wild
Radiant Health and Hormone Therapy
Kimberly Dewing, PA-C
Remedy 605
MOSAIC Medicine
Balanced Healthcare Functional Medicine
Black Hills IV Wellness Spa
Reset Weight
Cicily's Aesthetics
Nutrishop
Rapid City Health Professionals
SummaUp
Sioux Falls Secret for Weight Loss
LaVie Ideal Protein Virtual Clinic
Profile Plan - Personalized Weight Loss Plans (Virtual Location)
Trillion Health and Hormone Clinic
Sioux Falls Hypnosis
Health Concepts
Monument Health Lifestyle Medicine
Monument Health General Surgery and Bariatrics
Monument Health Rapid City Clinic, Flormann Street
Monument Health Primary Care NOW
Pure Medical Aesthetics, PLLC
Monument Health Endocrinology
EVOLVE Strength & Nutrition Coaching
Accelerate Wellness - Longevity Medicine Clinic
Well Beyond Functional Medicine
BeautyMed
ekin Nutrition Sioux Falls
Limitless Male Medical Clinic
Integrated Women's Health
Avera Comprehensive Weight Management — 41st & Holbrook
Frequently Asked Questions About GLP-1 Clinics in South Dakota
There are 43 GLP-1 weight loss clinics across 2 cities in South Dakota. The most providers are in Sioux Falls (22), Rapid City (21). The average patient rating is 4.9 out of 5.
South Dakota clinics prescribe Semaglutide, Tirzepatide, Liraglutide, Wegovy, Zepbound, Ozempic. The most commonly offered are semaglutide (15 clinics), tirzepatide (14 clinics), Semaglutide (11 clinics), Tirzepatide (11 clinics). Not all clinics list their full medication menu, so contact providers directly to confirm what they prescribe.
Yes. 23 of 43 clinics in South Dakota (53%) offer telehealth consultations. South Dakota has strong telehealth availability, making it easy to start treatment from home.
Monthly costs in South Dakota depend on whether you use brand-name or compounded medications. Brand-name GLP-1s (Wegovy, Zepbound) run $800–$1,400/month without insurance. Compounded semaglutide or tirzepatide from clinic programs typically costs $200–$500/month. Many telehealth clinics in South Dakota offer competitive bundled pricing that includes medication and follow-up visits.
Sioux Falls leads South Dakota with 22 GLP-1 clinics. Across the state, 43 clinics offer in-person visits and 23 offer telehealth.
GLP-1 Resources for South Dakota
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