South Dakota

40 GLP-1 Clinics in South Dakota (2026)

Find providers offering Ozempic, Wegovy, Mounjaro, Zepbound, and other GLP-1 medications in South Dakota. Compare ratings, check telehealth availability, and contact clinics directly.

Directory data refreshed: March 2026

40 Clinics
2 Cities
21 Telehealth
4.9 Avg Rating
$199.99 From / Month

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All 40 Clinics in South Dakota

Sponsored listings may appear first in default sorting. Ratings, reviews, and medication data are not affected by paid placement. How rankings work

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Researched Data compiled from Google Business Profile and the clinic’s public website. The clinic has not claimed this listing.
✓ Claimed The clinic owner manages this profile and can update its details.
★ Sponsored Paid placement. May appear first in default sorting. Ratings, reviews, and editorial rankings are not affected.
Data signals
Medication confirmed GLP-1 medications verified from the clinic's website or owner.
Pricing listed Starting price published by the clinic.
Features
Telehealth Virtual consultations available.
In-Person Accepts patients at a physical location.
Home Delivery Medication shipped to your home.
Free Consult Initial consultation at no cost.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Remedy 605 in Rapid City, SD

Remedy 605

Rapid City, SD
Wegovy Semaglutide Zepbound +1 more
From $500/mo Starting price for the most common medication plan. Actual cost may vary by medication, dose, and program.
In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner. Pricing listedStarting price published by the clinic.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
LIVE Hydration Spa Sioux Falls in Sioux Falls, SD

LIVE Hydration Spa Sioux Falls

Sioux Falls, SD
Semaglutide Tirzepatide
From $180/mo Starting price for the most common medication plan. Actual cost may vary by medication, dose, and program.
In-Person Home Delivery Free Consult
Medication confirmedGLP-1 medications verified from the clinic's website or owner. Pricing listedStarting price published by the clinic.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Refined Aesthetics in Sioux Falls, SD

Refined Aesthetics

Sioux Falls, SD
Semaglutide Tirzepatide
Telehealth In-Person Free Consult
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Encompass Wellness & Aesthetics in Sioux Falls, SD

Encompass Wellness & Aesthetics

Sioux Falls, SD
Semaglutide
Telehealth In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Cicily's Aesthetics in Rapid City, SD

Cicily's Aesthetics

Rapid City, SD
Semaglutide Tirzepatide
Telehealth In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Nutrishop in Rapid City, SD

Nutrishop

Rapid City, SD
Semaglutide Tirzepatide
Telehealth In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner.

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ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Novo Aesthetics in Sioux Falls, SD

Novo Aesthetics

Sioux Falls, SD
Semaglutide Tirzepatide
Telehealth In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Black Hills IV Wellness Spa in Rapid City, SD

Black Hills IV Wellness Spa

Rapid City, SD
Semaglutide Tirzepatide
Telehealth In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
The Confidence Collective in Sioux Falls, SD

The Confidence Collective

Sioux Falls, SD
Semaglutide Tirzepatide
Telehealth In-Person Home Delivery
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Gameday Men's Health Sioux Falls TRT, Peptide, and ED Clinic in Sioux Falls, SD

Gameday Men's Health Sioux Falls TRT, Peptide, and ED Clinic

Sioux Falls, SD
Semaglutide Tirzepatide
Telehealth In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Semaglutide Tirzepatide
Telehealth In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Era Health in Sioux Falls, SD

Era Health

Sioux Falls, SD
Semaglutide Tirzepatide
In-Person
Medication confirmedGLP-1 medications verified from the clinic's website or owner.
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.

Radiant Health and Hormone Therapy

Sioux Falls, SD
Contact clinic for medication details
Telehealth In-Person Free Consult
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
MOSAIC Medicine in Rapid City, SD

MOSAIC Medicine

Rapid City, SD
Contact clinic for medication details
In-Person
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
The Retreat at Cedar Creek in Sioux Falls, SD

The Retreat at Cedar Creek

Sioux Falls, SD
Contact clinic for medication details
In-Person
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Sanford Weight Management Center in Sioux Falls, SD

Sanford Weight Management Center

Sioux Falls, SD
Contact clinic for medication details
Telehealth In-Person
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.

Hormones Gone Wild

Sioux Falls, SD
Contact clinic for medication details
In-Person
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.

Balanced Healthcare Functional Medicine

Rapid City, SD
Contact clinic for medication details
In-Person
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.
Rapid City Health Professionals in Rapid City, SD

Rapid City Health Professionals

Rapid City, SD
Contact clinic for medication details
In-Person
ResearchedWe checked the basics using public information. The clinic has not claimed this listing yet.

Reset Weight

Rapid City, SD
Contact clinic for medication details
In-Person
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Frequently Asked Questions About GLP-1 Clinics in South Dakota

South Dakota Medicaid covers GLP-1s for type 2 diabetes. The state did not expand Medicaid under the ACA until 2023, and obesity-only GLP-1 coverage remains limited. Sanford Health Plans and Wellmark BCBS are the main commercial insurers, each with their own utilization management rules.

Sioux Falls holds most of South Dakota's GLP-1 providers, with smaller clusters in Rapid City and Aberdeen. Sanford Health and Monument Health both run weight management programs. Patients in western and central South Dakota frequently rely on telehealth to access GLP-1 care.

There are 40 GLP-1 weight loss clinics across 2 cities in South Dakota. The most providers are in Sioux Falls (21), Rapid City (19). The average patient rating is 4.9 out of 5.

South Dakota clinics prescribe Semaglutide, Tirzepatide, Wegovy, Zepbound, Ozempic, Mounjaro. The most commonly offered are semaglutide (14 clinics), tirzepatide (13 clinics), Semaglutide (9 clinics), Tirzepatide (9 clinics). Not all clinics list their full medication menu, so contact providers directly to confirm what they prescribe.

Yes. 21 of 40 clinics in South Dakota (53%) offer telehealth consultations. South Dakota has strong telehealth availability, making it easy to start treatment from home.

Based on 3 South Dakota clinics that publish pricing, programs start from $199.99/month. The typical range is $199.99 to $500/month depending on medication type and included services. Brand-name Wegovy or Zepbound runs $800 to $1,400/month without insurance. Compounded semaglutide or tirzepatide is generally cheaper. Many telehealth clinics bundle medication and visits into one monthly fee.

Sioux Falls leads South Dakota with 21 GLP-1 clinics. Across the state, 40 clinics offer in-person visits and 21 offer telehealth.