40 GLP-1 Clinics in South Dakota (2026)
Find providers offering Ozempic, Wegovy, Mounjaro, Zepbound, and other GLP-1 medications in South Dakota. Compare ratings, check telehealth availability, and contact clinics directly.
Cities in South Dakota
Get matched with clinics in South Dakota
Tell us your medication preference and visit type for personalized recommendations.
All 40 Clinics in South Dakota
Sponsored listings may appear first in default sorting. Ratings, reviews, and medication data are not affected by paid placement. How rankings work
What the badges mean
Full ranking methodology → • Pricing and medications can change. Always confirm with the clinic directly.
SummaUp
Monument Health Rapid City Clinic, Flormann Street
Monument Health General Surgery and Bariatrics
Health Concepts
EVOLVE Strength & Nutrition Coaching
Sioux Falls Hypnosis
Looking for the best fit in South Dakota?
Get matched with top clinics based on your preferences.
Get Matched →
Pure Medical Aesthetics, PLLC
Trillion Health and Hormone Clinic
Profile Plan - Personalized Weight Loss Plans (Virtual Location)
Sioux Falls Secret for Weight Loss
Monument Health Lifestyle Medicine
LaVie Ideal Protein Virtual Clinic
Accelerate Wellness - Longevity Medicine Clinic
BeautyMed
Well Beyond Functional Medicine
ekin Nutrition Sioux Falls
Limitless Male Medical Clinic
Integrated Women's Health
Avera Comprehensive Weight Management — 41st & Holbrook
Frequently Asked Questions About GLP-1 Clinics in South Dakota
South Dakota Medicaid covers GLP-1s for type 2 diabetes. The state did not expand Medicaid under the ACA until 2023, and obesity-only GLP-1 coverage remains limited. Sanford Health Plans and Wellmark BCBS are the main commercial insurers, each with their own utilization management rules.
Sioux Falls holds most of South Dakota's GLP-1 providers, with smaller clusters in Rapid City and Aberdeen. Sanford Health and Monument Health both run weight management programs. Patients in western and central South Dakota frequently rely on telehealth to access GLP-1 care.
There are 40 GLP-1 weight loss clinics across 2 cities in South Dakota. The most providers are in Sioux Falls (21), Rapid City (19). The average patient rating is 4.9 out of 5.
South Dakota clinics prescribe Semaglutide, Tirzepatide, Wegovy, Zepbound, Ozempic, Mounjaro. The most commonly offered are semaglutide (14 clinics), tirzepatide (13 clinics), Semaglutide (9 clinics), Tirzepatide (9 clinics). Not all clinics list their full medication menu, so contact providers directly to confirm what they prescribe.
Yes. 21 of 40 clinics in South Dakota (53%) offer telehealth consultations. South Dakota has strong telehealth availability, making it easy to start treatment from home.
Based on 3 South Dakota clinics that publish pricing, programs start from $199.99/month. The typical range is $199.99 to $500/month depending on medication type and included services. Brand-name Wegovy or Zepbound runs $800 to $1,400/month without insurance. Compounded semaglutide or tirzepatide is generally cheaper. Many telehealth clinics bundle medication and visits into one monthly fee.
Sioux Falls leads South Dakota with 21 GLP-1 clinics. Across the state, 40 clinics offer in-person visits and 21 offer telehealth.
GLP-1 Resources for South Dakota
Related Articles
The Wegovy Pill Is Here: How It Compares to Injections in 2026
Novo Nordisk launched the first oral GLP-1 for weight loss in 2026. How the Wegovy pill compares to injections on cost, results, and convenience.
medicationsSaxenda vs Ozempic: Which Is Better for Weight Loss?
Comparing liraglutide (Saxenda) to semaglutide (Ozempic/Wegovy) for weight loss: effectiveness, cost, injection frequency, and side effects.
medicationsSwitching from Ozempic to Mounjaro: What to Expect
Considering a switch from semaglutide to tirzepatide? Here's how the transition works, dose equivalencies, and what patients typically experience.